Chromosome Mutations Lab

Simplified model for learning. Inversions: four chromatids, at most one crossover per meiosis, a dicentric bridge breaks at a random point and an acentric fragment is always lost. Random mode puts a crossover inside the loop with the chance you set; otherwise half the meioses get a crossover outside the inversion. Translocations: each line stands for a pair of sister chromatids, crossovers are not shown (in the arms they swap alleles but do not change balance), and random segregation uses alternate 50 percent, adjacent 1 40 percent and adjacent 2 10 percent; real frequencies vary. Robertsonian random mode treats the three segregation patterns as equally likely, which overestimates real risks. Gene letters are made up.

Problems are randomly generated for practice. Probabilities can be typed as a fraction (1/4), a decimal (0.25) or a percent (25%). Percent answers can be typed with or without the % sign. Gene letters, people and band numbers are made up unless a problem names a real syndrome.