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General Biology I · Modules 1 to 16

See It: General Biology I

See biology happen at every scale. Each module has an animated walkthrough that links the organism, the cell and the molecule, with worked examples for every calculation, and a Lab with simulators, a practice trainer, a sorting game and real-world data scenarios. Everything runs in your browser on a computer, tablet or phone. No login, nothing graded.

How to use this: open the walkthrough first and go at your own pace with the arrow keys or Next. Then open the Lab: run the simulator, practice in the trainer with its hints and worked solutions, and try the real-world scenarios. Use the tools bar at the top of each page to pause the animations, slow them down, have the text read aloud, or get a written description of each picture. Nothing here is graded.

Module 1 Chemistry of life

Elements and isotopes, bonds and interactions, water's properties, pH and buffers, carbon and functional groups.

Module 2 Biological macromolecules

Dehydration and hydrolysis, carbohydrates, lipids, the four levels of protein structure, and nucleic acids.

Module 3 Cell structure

Microscopy, surface area to volume, prokaryotic vs eukaryotic cells, the endomembrane system, mitochondria and chloroplasts, the cytoskeleton and cell junctions.

Module 4 Membranes and transport

Fluid mosaic model, diffusion and osmosis, tonicity and water potential, channels and carriers, the sodium potassium pump, cotransport and bulk transport.

Module 5 Energy, enzymes and metabolism

Thermodynamics, free energy, ATP and energy coupling, activation energy, enzyme kinetics, inhibition and allosteric regulation.

Module 6 Cellular respiration

Redox, glycolysis, pyruvate oxidation, the citric acid cycle, the electron transport chain and chemiosmosis, ATP yield, fermentation and regulation.

Module 7 Photosynthesis

Chloroplasts, light and pigments, photosystems and electron flow, the Calvin cycle, photorespiration, C4 and CAM plants, and limiting factors.

Module 8 Cell communication

Local and long-distance signals, reception, G protein coupled receptors, receptor tyrosine kinases, second messengers, amplification, responses and apoptosis.

Module 9 The cell cycle and mitosis

Chromosomes and counting rules, cell cycle phases, the stages of mitosis, cytokinesis, cyclins and checkpoints, and cancer.

Module 10 Meiosis and sexual life cycles

Homologs and ploidy, three life cycles, meiosis I and II, crossing over, independent assortment, nondisjunction, and gametogenesis.

Module 11 Mendelian genetics

Segregation and independent assortment, Punnett squares and probability, chi square, dominance patterns, epistasis, polygenic traits and pedigrees.

Module 12 Chromosomes and inheritance patterns

Morgan's flies, sex determination and sex linkage, X inactivation, linkage and gene mapping, chromosomal alterations, imprinting and mitochondrial inheritance.

Module 13 DNA structure and replication

The search for the genetic material, the double helix, Meselson and Stahl, the replication fork, proofreading and repair, telomeres and chromatin.

Module 14 Gene expression

The genetic code, transcription, RNA processing and splicing, translation, protein targeting and mutations.

Module 15 Gene regulation

The lac and trp operons, chromatin and epigenetics, eukaryotic transcription control, RNA-level control, development and cancer genetics.

Module 16 Biotechnology

Cloning with plasmids, PCR, gel electrophoresis, sequencing, gene expression tools, CRISPR, GMOs, gene therapy, stem cells and DNA forensics.