Pain Neuroscience Lab

How the model works: tissue input sets nociceptor traffic. Poor sleep, ongoing stress and fear raise a "sensitivity" level that amplifies spinal transmission and can add signal even with no tissue input, like nociplastic pain. Touch and movement send A beta input that partly closes the spinal gate. Movement, expecting relief and sudden danger strengthen the descending brakes; stress, fear, expecting harm and poor sleep strengthen the boosters. Fear, stress and expectation also change how threatening the brain judges the signal. All weights are invented for teaching.

Predict first, then watch the picture show what happens. In predict items the knobs are a teaching model, not a measurement. Calculation items use rounded textbook values.