Pick a drug and watch where it lands. Arachidonic acid (the zigzag) is cut out of cell membranes and fed to two enzymes. COX-1 makes the housekeeping prostaglandins that protect the stomach, help platelets clump and keep blood flowing to the kidney. COX-2 makes the prostaglandins of an inflamed joint, pain and fever. Then move the clock to see which effects fade and which stay.
Your patient had surgery this morning and rates the pain 8 out of 10. One opioid dose has just been given. Start the clock and watch the sedation level, breathing rate and oxygen saturation. Add a second dose, a second sedating drug or an older patient, and practise when to hold the opioid and when to give naloxone. Opioid amounts are relative teaching units, not doses.
Wrong answers are fine here. Each one tells you why.
Your job
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