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Pathophysiology · Modules 1 to 14

See It: Pathophysiology

See how 205 diseases and conditions actually happen. Each module has an animated walkthrough (normal, what breaks, how the body compensates, and why the patient has each sign) and a Case Lab with simulators and patient cases. Everything runs in your browser on a computer, tablet or phone. No login, nothing graded.

How to use this: open the walkthrough first and go at your own pace with the arrow keys or Next. Then try the Case Lab: move the sliders and watch the patient change, and work the cases. Use the tools bar at the top of each page to pause the animations, slow them down, have the text read aloud, or get a written description of each picture.

Module 1 Fluids and electrolytes

Where water goes wrong, and the electrolytes and acid-base numbers that tell you.

Start here · Animated walkthroughFluids and electrolytes WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 1 Case LabFluid Shift Simulator, ABG Interpreter, 7 patient cases, and compare-and-sort rounds.

Module 2 Pathogens and immune disorders

How germs cause disease, and what happens when the immune system overreacts, attacks itself or fails.

Start here · Animated walkthroughPathogens and immune disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 2 Case LabHIV Course Simulator, Anaphylaxis Simulator, 8 patient cases, and sorting rounds.

Module 3 Cell injury, inflammation and cancer

How cells adapt, get hurt and die, how inflammation works, and how cancer grows and spreads.

Start here · Animated walkthroughCell injury, inflammation and cancer WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 3 Case LabTissue Stress Simulator, Tumor Growth Lab, 7 patient cases, and compare-and-contrast rounds.

Module 4 Sepsis, shock, pain and wound healing

When the body cannot feed its tissues, why fever and pain happen, and how wounds close.

Start here · Animated walkthroughSepsis, shock, pain and wound healing WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 4 Case LabShock Simulator, 8 patient cases, signature sort and cascade-ordering games.

Module 5 Neurological disorders

Pressure in the skull, head injury, stroke, seizures, and the diseases of myelin, the NMJ and dying neurons.

Start here · Animated walkthroughNeurological disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 5 Case LabNerve Signal Simulator, Skull Pressure Simulator, 8 patient cases, and sorting rounds.

Module 6 Musculoskeletal and skin disorders, burns

Broken and weakened bones, sore joints, muscle and nerve problems, burns and skin disease.

Start here · Animated walkthroughMusculoskeletal and skin disorders, burns WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 6 Case LabBurn Simulator, Bone Remodeling Simulator, 8 patient cases, and compare-and-contrast rounds.

Module 7 Genetic disorders

How a change in DNA becomes a disease, and how it passes through families.

Start here · Animated walkthroughGenetic disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 7 Case LabInheritance Simulator, Sickle Cell Simulator, 7 patient cases, and sorting rounds.

Module 8 Endocrine disorders

Diabetes and its emergencies, ADH problems, thyroid, adrenal and growth hormone disorders.

Start here · Animated walkthroughEndocrine disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 8 Case LabGlucose and Insulin Simulator, Hormone Axis Simulator, 8 patient cases, and compare rounds.

Module 9 Blood disorders and vascular disease

Anemias, too many cells, bleeding and clotting problems, and diseased vessels.

Start here · Animated walkthroughBlood disorders and vascular disease WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 9 Case LabAnemia and CBC Simulator, Pressure and Flow Simulator, 8 patient cases, and sorting rounds.

Module 10 Cardiac disorders

Coronary disease and heart attack, heart failure, rhythm problems, valves and the heart's lining.

Start here · Animated walkthroughCardiac disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 10 Case LabHeart Failure Simulator, Rhythm Simulator, 8 patient cases, and compare-and-contrast rounds.

Module 11 Renal and urinary disorders

Kidney injury, chronic kidney disease, glomerular disease, infection and stones.

Start here · Animated walkthroughRenal and urinary disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 11 Case LabNephron and GFR Simulator, Filter Damage Simulator, 8 patient cases, and sorting rounds.

Module 12 Respiratory disorders

Airways that narrow, alveoli that fill or break, and lungs that cannot move air or blood.

Start here · Animated walkthroughRespiratory disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 12 Case LabSpirometry Simulator, V/Q Simulator, 8 patient cases, and compare-and-sort rounds.

Module 13 Gastrointestinal disorders

From reflux and ulcers to bowel inflammation, malabsorption, the acute abdomen and the pancreas.

Start here · Animated walkthroughGastrointestinal disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 13 Case LabStomach Defense Simulator, Villi Absorption Simulator, 7 patient cases, and compare rounds.

Module 14 Liver, biliary and reproductive disorders

Jaundice, hepatitis, cirrhosis and gallstones, plus common female and male reproductive disorders.

Start here · Animated walkthroughLiver, biliary and reproductive disorders WalkthroughWatch each disease happen step by step: normal, what breaks, how the body compensates, and why the patient has each sign. Simulators + casesModule 14 Case LabCirrhosis Simulator, Jaundice Simulator, 8 patient cases, and sorting rounds.