Skin, Eye and Respiratory Lab

Part 1: Flu Drift and Shift Simulator

Season 0

Immune from past infectionProtected by vaccineInfected this seasonSusceptibleImmunity at season start

1. How the virus changes

Antigenic drift every year (small H and N changes)

A shift swaps in a whole new H from a bird flu virus by reassortment.

2. Protect the town

Vaccine coverage 30%

0%40%80%

The vaccine is updated each year for drift and protects about half of the people who get it, for one season. After a shift, it is not ready for the first season.

Season readouts
Measure	Value

Challenges

Part 2: TB Granuloma Simulator

Speed Month 0

Drug-sensitive TBResistant (MDR) TBGranuloma wallOn treatment

1. The person's immune system

Cell-mediated immunity 90%

weakstrong

2. Treatment

Doses taken 100%

20%60%100%

TB readouts
Measure	Value

Skin, Eye and Respiratory Infections Lab

Part 1: Flu Drift and Shift Simulator

Part 2: TB Granuloma Simulator

Part 3: Patient Case Files

Part 4: Sort the Microbes