| Measure | Value |
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How the model works: the hypothalamus sends TRH to the pituitary, the pituitary sends TSH to the thyroid, and the thyroid sends T4 to the body. Free T4 brakes the pituitary and hypothalamus (negative feedback). When the thyroid itself fails, the brake weakens and TSH climbs. When the pituitary or hypothalamus fails, TSH cannot climb, so T4 falls with a low or normal TSH.
The picture splits the key term into its parts, or shows the chart line the question is about. Meanings appear after you answer.
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Fictional adults and simplified findings. For learning only, not medical advice.
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