Chromosomal Disorders

When the chromosome count is off · Week 7
A nondisjunction error in meiosis can leave an egg or sperm with an extra chromosome. That is a trisomy. It can also leave one missing, which is a monosomy. A karyotype is a photo of all the chromosomes, and it shows the problem. Click each classic disorder.

The karyotype clue

This is the chromosome pair that matters. Normal is two copies. These disorders have three, or just one.
Pick a disorder.
Pick a disordertrisomy & monosomy

What it is

Count it out: a trisomy is an extra chromosome, three instead of two. Down syndrome (T21) and Klinefelter (XXY) are trisomies. A monosomy is a missing one. Turner syndrome is the example, with a single X, or "XO".