Six lessons cover this chapter. Open any of them on its own below, or meet it in place inside chapter 7 of the book. Tick a lesson off once you can predict what it will do before you touch it.
1
The Central Dogma: DNA → RNA → Protein
Run a gene from DNA to RNA to protein. Then jam one step with a drug.
2
Point Mutations: One Base, One Protein
Swap, add or drop one base. See the codons and the protein change.
3
Horizontal Gene Transfer: Three Ways to Share DNA
Run the three sharing routes side by side. Then block each one in turn.
4
Anatomy of an R-Plasmid
Build an R plasmid gene by gene. Then test it against four drugs.
5
Selective Pressure: Why Survivors Take Over
Dose a dish of bacteria. Watch the resistant few take over, round by round.
6
Conjugation: Spreading Resistance Cell to Cell
Build the pilus, nick the plasmid, and pump one strand into the next cell.