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Microbiology · Chapter 1

Colonization, Infection, Disease

The same microbe can be harmless, invading, or making someone ill. The difference decides whether anything gets treated. Set the dose, pick a barrier, choose how strong the defenses are, then run the week and watch the state change.

A patch of tissue redrawn every time you change a setting

Tissue cross section

Set the dose, the barrier, and the defenses. Then run the week.

Seven days of it microbes in the tissue against the host response

Invasion and response over seven days
Microbes inside the tissue Host response
Colonizationset the controls and watch the state change
Microbe present?—
Host responding?—
Symptoms?—

The barrier

The body's defenses
Starting dose 100 thousand microbes
Day 3

Readings

0microbes inside the tissue
On the surface —
Host response none
Signs and symptoms none
What a swab would show —